| Seq Identity | Jmol Display | PDB Title |
|---|
| 2F8G | 100% |  | HIV-1 PROTEASE MUTANT I50V COMPLEXED WITH INHIBITOR TMC114 |
|---|
| 2IEN | 99% | | CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) |
|---|
| 3TKW | 99% | | CRYSTAL STRUCTURE OF HIV PROTEASE MODEL PRECURSOR/DARUNAVIR COMPLEX |
|---|
| 3CYW | 98% | | EFFECT OF FLAP MUTATIONS ON STRUCTURE OF HIV-1 PROTEASE AND INHIBITION BY SAQUINAVIR AND DARUNAVIR |
|---|
| 2F80 | 98% | | HIV-1 PROTEASE MUTANT D30N COMPLEXED WITH INHIBITOR TMC114 |
|---|
| 3PWM | 98% | | HIV-1 PROTEASE MUTANT L76V WITH DARUNAVIR |
|---|
| 2IEO | 98% | | CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT I84V WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) |
|---|
| 3D20 | 98% | | CRYSTAL STRUCTURE OF HIV-1 MUTANT I54V AND INHIBITOR DARUNAVIA |
|---|
| 2IDW | 98% | | CRYSTAL STRUCTURE ANALYSIS OF HIV-1 PROTEASE MUTANT V82A WITH A POTENT NON-PEPTIDE INHIBITOR (UIC-94017) |
|---|
| 2HS1 | 98% | | ULTRA-HIGH RESOLUTION X-RAY CRYSTAL STRUCTURE OF HIV-1 PROTEASE V32I MUTANT WITH TMC114 (DARUNAVIR) INHIBITOR |
|---|
| 2HS2 | 98% | | CRYSTAL STRUCTURE OF M46L MUTANT OF HIV-1 PROTEASE COMPLEXED WITH TMC114 (DARUNAVIR) |
|---|
| 2F81 | 98% | | HIV-1 PROTEASE MUTANT L90M COMPLEXED WITH INHIBITOR TMC114 |
|---|
| 3BVB | 98% | | CYSTAL STRUCTURE OF HIV-1 ACTIVE SITE MUTANT D25N AND INHIBITOR DARUNAVIR |
|---|
| 3D1Z | 98% | | CRYSTAL STRUCTURE OF HIV-1 MUTANT I54M AND INHIBITOR DARUNAVIR |
|---|
| 3JW2 | 98% | | HIV-1 PROTEASE MUTANT G86S WITH DARUNAVIR |
|---|
| 5KQY | 97% | | PROTEASE E35D-DRV |
|---|
| 4DQB | 96% | | CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 PROTEASE IN COMPLEX WITH DRV |
|---|
| 3S53 | 96% | | HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P212121 |
|---|
| 3S54 | 96% | | HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUNAVIR IN SPACE GROUP P21212 |
|---|
| 5E5J | 96% | | JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 6.0 |
|---|
| 5E5K | 96% | | JOINT X-RAY/NEUTRON STRUCTURE OF HIV-1 PROTEASE TRIPLE MUTANT (V32I, I47V,V82I) WITH DARUNAVIR AT PH 4.3 |
|---|
| 4DQH | 95% | | CRYSTAL STRUCTURE OF (R14C/E65C) HIV-1 PROTEASE IN COMPLEX WITH DRV |
|---|
| 6DH6 | 95% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE NL4-3 I50V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 6DGX | 94% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH DARUNAVIR |
|---|
| 4DQE | 94% | | CRYSTAL STRUCTURE OF (G16C/L38C) HIV-1 PROTEASE IN COMPLEX WITH DRV |
|---|
| 4DQF | 94% | | CRYSTAL STRUCTURE OF (G16A/L38A) HIV-1 PROTEASE IN COMPLEX WITH DRV |
|---|
| 4DQC | 94% | | CRYSTAL STRUCTURE OF (G16C/L38C) HIV-1 PROTEASE IN COMPLEX WITH DRV |
|---|
| 6OPS | 94% | | HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH DARUNAVIR |
|---|
| 4HLA | 94% | | CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH DARUNAVIR |
|---|
| 6OOS | 93% | | HIV-1 PROTEASE NL4-3 L90M MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 6OOU | 93% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE NL4-3 L89V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 5KR1 | 93% | | PROTEASE PR5-DRV |
|---|
| 6DH0 | 93% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE NL4-3 I84V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 6DH3 | 93% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE NL4-3 V82I MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 4LL3 | 93% | | STRUCTURE OF WILD-TYPE HIV PROTEASE IN COMPLEX WITH DARUNAVIR |
|---|
| 6OOT | 92% | | HIV-1 PROTEASE NL4-3 L89V, L90M MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 6OPT | 92% | | HIV-1 PROTEASE NL4-3 V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 1T7I | 91% | | THE STRUCTURAL AND THERMODYNAMIC BASIS FOR THE BINDING OF TMC114, A NEXT-GENERATION HIV-1 PROTEASE INHIBITOR. |
|---|
| 7MAS | 91% | | DRUG RESISTANT HIV-1 PROTEASE (L10F, M46I, I50V, F53L, L63P, G73S) IN COMPLEX WITH DRV |
|---|
| 3OXW | 91% | | CRYSTAL STRUCTURE OF HIV-1 I50V, A71V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR |
|---|
| 1T3R | 91% | | HIV PROTEASE WILD-TYPE IN COMPLEX WITH TMC114 INHIBITOR |
|---|
| 4Q1W | 91% | | MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE |
|---|
| 4Q1X | 91% | | MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE |
|---|
| 4Q1Y | 91% | | MUTATIONS OUTSIDE THE ACTIVE SITE OF HIV-1 PROTEASE ALTER ENZYME STRUCTURE AND DYNAMIC ENSEMBLE OF THE ACTIVE SITE TO CONFER DRUG RESISTANCE |
|---|
| 3OY4 | 91% | | CRYSTAL STRUCTURE OF HIV-1 L76V PROTEASE IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR. |
|---|
| 6OPU | 90% | | HIV-1 PROTEASE NL4-3 K45I, M46I, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 7MAP | 88% | | DRUG RESISTANT HIV-1 PROTEASE (L10I, V32I, L33F, K45I, M46I, I50V, A71V, V82I, I84V) IN COMPLEX WITH DRV |
|---|
| 7MAQ | 88% | | DRUG RESISTANT HIV-1 PROTEASE (L10F, V32I, L33F, K45I, A71V, V82I, I84V) IN COMPLEX WITH DRV |
|---|
| 3LZS | 88% | | CRYSTAL STRUCTURE OF HIV-1 CRF01_AE PROTEASE IN COMPLEX WITH DARUNAVIR |
|---|
| 3EKT | 88% | | CRYSTAL STRUCTURE OF THE INHIBITOR DARUNAVIR (DRV) IN COMPLEX WITH A MULTI-DRUG RESISTANT HIV-1 PROTEASE VARIANT (L10F/G48V/I54V/V64I/V82A) (REFER: FLAP+ IN CITATION.) |
|---|
| 6OPV | 87% | | HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 3LZU | 87% | | CRYSTAL STRUCTURE OF A NELFINAVIR RESISTANT HIV-1 CRF01_AE PROTEASE VARIANT (N88S) IN COMPLEX WITH THE PROTEASE INHIBITOR DARUNAVIR. |
|---|
| 6OPX | 86% | | HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, L76V, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR |
|---|
| 4NPT | 85% | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE MULTIPLE MUTANT P51 COMPLEXED WITH DARUNAVIR |
|---|